The reporter learned yesterday from the Department of Science and Technology of Zhejiang Province that the solid fermentation and dosage form processing technology research project of the major scientific and technological special project of Zhejiang Province, the microbiological herbicide Fusarium oxysporum (C. oxysporum), was undertaken by Yu Liuqing and other researchers of the China National Rice Research Institute. At present, the production workshop of 1% Klebsiella spore powder has been initially built at Zhejiang Tianyi Agrochemical Co., Ltd., which means that Zhejiang Province has the first microbial herbicide product and takes an important step in industrial development.
Since the application of chemical herbicides in the world, it is still the main means of weed control in farmland. However, over time, the drawbacks brought about by the large-scale application of chemical herbicides have become increasingly apparent. Against this background, microbial herbicides with higher selectivity, no pollution to the environment, and less resistance to drug resistance are highly valued by scientists from various countries. Some microbial herbicide varieties have been successfully developed abroad.
China is one of the earliest countries in the world to start applying microbial pathogens to develop microbial herbicides. The China Rice Research Institute has accumulated rich experience and achievements in the field of microbial herbicides, especially in the industrialization of Klebsiella. In 2008, the Zhejiang Science and Technology Agency included the research on the solid fermentation and dosage form processing technology of the microbial herbicide Klebsiella spp. as a major provincial science and technology project, which was handed over to the China National Rice Research Institute for implementation.
In the past three years, Yu Liuqing’s research team led the project team to systematically study the solid fermentation sporulation technology and dosage form processing technology for the problems of low spore yield and unstable weeding effect in the industrial production of Gramineous plants. A series of innovations. In the aspect of solid fermentation sporulation technology research, the project team determined the best culture and technological conditions for solid-phase sporulation and sporulation in the pilot-scale trays. Spore yield reached 1.5×107 cells/g dry medium, which was an order of magnitude higher than before. On this basis, they further determined the optimal culture and processing conditions for solid-phase sporulation and sporulation of the pilot-scale cloth bag. The spore yield reached 1.7×107 cells/g dry medium, making this technology possible for large-scale industrial production. .
At the same time, the researchers also made breakthroughs in the processing technology of Gramineae and Gramineae, and successfully developed the Gram-negative spore suspension agent and the 1% Kleboptera spore powder, completed the toxicological test of the preparation, and started the countrywide field. The drug efficacy test prepared scientific data for the first registration of 1% Klebsiella spore powder in China. On this basis, they also established a joint research platform for production, education and research with Zhejiang Tianyi Agrochemical Co., Ltd. to further promote the industrialization of Gramineous mold. At present, a 1% preparation plant for Trichoderma spores powder has been initially established.
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